Placental TGF-Beta
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Growth Factor ->
Transforming Growth Factor ->
Transforming Growth Factor-Beta -> Placental TGF-Beta
Placental TGF-Beta Definition
Expressed in activated, but not resting, macrophages and in placenta, prostate, colon, and kidney by human PLAB Gene (BMP/TGF-Beta Family), 308-aa 34-kDa (precursor) Placental TGF-Beta is processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in a disulfide-linked homodimeric secreted mature protein of 224 amino acids. PLAB regulates tissue differentiation and maintenance and reduces the growth of granulocytes and macrophages. Unlike most TGFB superfamily members, in which the amino acid sequence is completely conserved, PLAB shares only 70% amino acid identity with its rodent counterparts. (NCI)
Placental TGF-Beta Synonyms
Placental TGF-Beta, GDF15, Growth/Differentiation Factor 15, MIC1, Macrophage Inhibitory Cytokine-1, NAG1, NRG1, NSAID-Activated Protein 1, NSAID-Regulated Protein 1, Nonsteroidal Anti-Inflammatory Drug-Activated Protein 1, PDF, PTGF-Beta, PTGFB, Placental Bone Morphogenic Protein, Prostate Differentiation Factor
Terms in Placental TGF-Beta category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.