Plasminogen Activator Inhibitor-2
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Plasminogen Activator Inhibitor-2 Definition
Expressed in keratinocytes, monocytes, macrophages, placenta, and trophoblast by human SERPINB2 Gene (Serpin Family), 415-aa 47-kDa (predicted, unglycosylated) cytoplasmic Plasminogen Activator Inhibitor 2 is a specific inhibitor of urokinase-type plasminogen activator thought to regulate plasminogen activation in the extravascular compartment and to have a possible role in placental maintenance or embryo development. The primary intracellular distribution of SERPINB2 may also indicate a regulatory role in a protease-dependent cellular process such as apoptosis. (NCI)
Plasminogen Activator Inhibitor-2 Synonyms
Plasminogen Activator Inhibitor-2, Arginine-Serpin, Monocyte Arg-Serpin, PAI, PAI-2, PLANH2, Placental Plasminogen Activator Inhibitor, Plasminogen Activator Inhibitor Type II, SERPINB2, Serine or Cysteine Proteinase Inhibitor Clade B Member 2, Urokinase Inhibitor
Terms in Plasminogen Activator Inhibitor-2 category
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