Cancer Terms

Plasminogen Activator Inhibitor-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Enzyme Inhibitor Protein -> Serine Proteinase Inhibitor -> Serpin -> Plasminogen Activator Inhibitor -> Plasminogen Activator Inhibitor-2

Plasminogen Activator Inhibitor-2 Definition

Expressed in keratinocytes, monocytes, macrophages, placenta, and trophoblast by human SERPINB2 Gene (Serpin Family), 415-aa 47-kDa (predicted, unglycosylated) cytoplasmic Plasminogen Activator Inhibitor 2 is a specific inhibitor of urokinase-type plasminogen activator thought to regulate plasminogen activation in the extravascular compartment and to have a possible role in placental maintenance or embryo development. The primary intracellular distribution of SERPINB2 may also indicate a regulatory role in a protease-dependent cellular process such as apoptosis. (NCI)

Plasminogen Activator Inhibitor-2 Synonyms

Plasminogen Activator Inhibitor-2, Arginine-Serpin, Monocyte Arg-Serpin, PAI, PAI-2, PLANH2, Placental Plasminogen Activator Inhibitor, Plasminogen Activator Inhibitor Type II, SERPINB2, Serine or Cysteine Proteinase Inhibitor Clade B Member 2, Urokinase Inhibitor

Terms in Plasminogen Activator Inhibitor-2 category



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