Platelet Activating Factor Suppression

Cancer Terms -> Biological Process -> Subcellular Process -> Biochemical Process -> Immunologic Factor Suppression -> Platelet Activating Factor Suppression

Platelet Activating Factor Suppression Definition

By increased degradation, or decreased production or receptor binding, Platelet Activating Factor Suppression involves interference with, or restraint of, the activity of a phospholipid derivative (platelet activating factor) formed by platelets, basophils, neutrophils, monocytes, and macrophages that acts as a potent agent of platelet aggregation, inflammation, neutrophil activity, prostaglandin synthesis, and systemic anaphylaxis: hypotension, thrombocytopenia, neutropenia, and bronchoconstriction.