Cancer Terms

Polyamine Inhibitory Agent

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Polyamine Inhibitory Agent

Polyamine Inhibitory Agent Definition

A compound that inhibits the synthesis of the naturally occurring polyamines, intracellular compounds that bind to DNA and play a critical role in cell division, differentiation and membrane function. These inhibitors affect the activity of enzymes like ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMD) that are involved in the biosynthesis of polyamines. A reduction in intracellular polyamine concentration may lead to a decreased cell growth.

Polyamine Inhibitory Agent Synonyms

Polyamine Synthesis Inhibitor, Polyamine Inhibitor

Terms in Polyamine Inhibitory Agent category



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