Proteasome-26S Subunit Non-ATPase-10
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Proteasome-26S Subunit Non-ATPase-10 Definition
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. This protein is a non-ATPase subunit of the 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. (from LocusLink)
Proteasome-26S Subunit Non-ATPase-10 Synonyms
Proteasome 26S Subunit Non-ATPase 10, 26S Proteasome Regulatory Subunit p28, Gankyrin, Hepatocellular Carcinoma-Associated Protein p28-II, PSMD10
Terms in Proteasome-26S Subunit Non-ATPase-10 category
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