Protein Kinase B

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> Protein Kinase B

Protein Kinase B Definition

Expressed in diverse tissues, Protein Kinase B (AKT/RAC Family) is a group (Alpha, Beta and Gamma) of cytoplasmic serine/threonine enzymes that covalently transfer the terminal, gamma phosphate group from ATP to a variety of substrate proteins and regulate cell signaling responses to insulin, PDGF, and IGF1 (through PI3K) involved in cell survival, cell proliferation, differentiation, apoptosis, glycogen synthesis, and glucose uptake.

Protein Kinase B Synonyms

Protein Kinase B, AKT

Terms in Protein Kinase B category

Protein Kinase-B Beta
Protein Kinase-B Gamma
RAC-Alpha Serine-Threonine Kinase