Protein Kinase-A C-Gamma

Cancer Terms -> Gene Product -> Protein or Riboprotein Complex -> Protein Kinase-A -> Protein Kinase-A C-Gamma

Protein Kinase-A C-Gamma Definition

Encoded by human PRKACG Gene (cAMP Ser/Thr Protein Kinase Family), 350-aa 40-kDa Protein Kinase A C-Gamma (may be testis-specific) is a catalytic subunit of tetrameric inactive cytoplasmic holoenzyme Protein Kinase A. Homo- or heterodimeric regulatory subunits of inactive PKA holoenzyme are associated with two catalytic subunits. Most cellular effects of cAMP are mediated through PKA. cAMP-induced dissociation of holoenzyme releases a dimer of cAMP-bound regulatory subunits and free monomeric catalytic subunits that serine/threonine phosphorylate many cytoplasmic and nuclear substrates. (NCI)

Protein Kinase-A C-Gamma Synonyms

Protein Kinase A C-Gamma, KAPG, PKA C-Gamma, PRKACG, cAMP-Dependent Protein Kinase Gamma

Protein Kinase-A C-Gamma

Protein Kinase-A C-Gamma Definition

Protein Kinase-A C-Gamma Synonyms

Terms in Protein Kinase-A C-Gamma category