Protein Kinase-B Gamma
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Enzyme ->
Transferase ->
Phosphotransferase ->
Kinase ->
Protein Kinase ->
Serine-Threonine Protein Kinase ->
Protein Kinase B -> Protein Kinase-B Gamma
Protein Kinase-B Gamma Definition
Highly expressed in brain, lung, kidney and fetal heart, liver, brain by human AKT3 Gene (AKT/RAC Family) as alternative isoforms 1 (479-aa, 55.8-kD) and 2 (465-aa; shorter C-terminus), cytoplasmic Protein Kinase B Gamma contains a PH domain that binds PI(3)K alpha and promotes plasma membrane translocation after cell stimulation. Fully active when phosphorylated on threonine and serine residues, AKT3 phosphorylates several proteins to regulate cell signaling responses to insulin, PDGF, and IGF1 involved in cell proliferation, differentiation, apoptosis, glycogen synthesis, and glucose uptake. (NCI)
Protein Kinase-B Gamma Synonyms
Protein Kinase B Gamma, AKT3, V-Akt Murine Thymoma Viral Oncogene Homolog 3
Terms in Protein Kinase-B Gamma category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.