Protein Phosphatase 2A Complex
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Protein Phosphatase 2A Complex Definition
PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression.
Protein Phosphatase 2A Complex Synonyms
Protein Phosphatase 2A, PP2A
Terms in Protein Phosphatase 2A Complex category
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