Protein Phosphatase-1 Catalytic Subunit Alpha

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Phosphatase -> Phosphoprotein Phosphatase -> Protein Serine-Threonine Phosphatase -> Protein Phosphatase-1 Catalytic Subunit Alpha

Protein Phosphatase-1 Catalytic Subunit Alpha Definition

Expressed by human PPP1CA Gene (PP1 Family), cytoplasmic Protein Phosphatase 1 Catalytic Subunit Alpha is one of 3 catalytic subunits (A, B, or C) of PP1 folded by IPP2 and GSK3 and then complexed to various targeting or regulatory subunits. PPP1CA is inhibited by IPP1 and IPP2. Protein phosphorylation is crucial in the regulation of many cellular functions; the level of phosphorylation is controlled by the actions of opposing kinases and phosphatases. PP1 is a major serine/threonine-protein phosphatase essential for cell division, regulation of glycogen metabolism, muscle contractility protein synthesis, regulation of ionic conductances, and long-term synaptic plasticity/memory. PPP1CA may dephosphorylate postsynaptic density-associated Ca++/calmodulin dependent protein kinase II. (NCI)

Protein Phosphatase-1 Catalytic Subunit Alpha Synonyms

Protein Phosphatase 1 Catalytic Subunit Alpha, PPP1A, PPP1CA, Serine/Threonine Protein Phosphatase PP1-Alpha 1 Catalytic Subunit

Protein Phosphatase-1 Catalytic Subunit Alpha

Protein Phosphatase-1 Catalytic Subunit Alpha Definition

Protein Phosphatase-1 Catalytic Subunit Alpha Synonyms

Terms in Protein Phosphatase-1 Catalytic Subunit Alpha category