Protein Phosphatase-2 Regulatory Subunit-B Alpha
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Protein Phosphatase Regulatory Protein -> Protein Phosphatase-2 Regulatory Subunit-B Alpha
Protein Phosphatase-2 Regulatory Subunit-B Alpha Definition
Ubiquitously expressed (heart and skeletal muscle highest) by human PPP2R5A Gene (PP2A Subunit B Family), serine phosphorylated 486-aa 56-kDa cytoplasmic Protein Phosphatase 2 Regulatory Subunit B Alpha is a subunit of PP2A. A major Ser/Thr phosphatase implicated in negative control of cell growth and division, PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression. (NCI)
Protein Phosphatase-2 Regulatory Subunit-B Alpha Synonyms
Protein Phosphatase 2 Regulatory Subunit B Alpha, PP2A B Subunit B Prime Alpha, PP2A B Subunit B56 Alpha, PP2A B Subunit PR61 Alpha, PP2A B Subunit R5 Alpha, PPP2R5A, Protein Phosphatase 2A Regulatory Subunit B56 Alpha, Serine/Threonine Protein Phosphatase 2A 56 kDa Regulatory Subunit Alpha
Terms in Protein Phosphatase-2 Regulatory Subunit-B Alpha category
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