Protein Phosphatase-2 Regulatory Subunit-B Beta
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Protein Phosphatase Regulatory Protein -> Protein Phosphatase-2 Regulatory Subunit-B Beta
Protein Phosphatase-2 Regulatory Subunit-B Beta Definition
Ubiquitously expressed (highest in brain) as 2 isoforms by human PPP2R5B Gene (PP2A Subunit B Family), serine phosphorylated cytoplasmic Protein Phosphatase 2 Regulatory Subunit B Beta is a regulatory subunit of PP2A. A major Ser/Thr phosphatase implicated in negative control of cell growth and division, PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression. (NCI)
Protein Phosphatase-2 Regulatory Subunit-B Beta Synonyms
Protein Phosphatase 2 Regulatory Subunit B Beta, PP2A B Subunit B Prime Beta, PP2A B Subunit B56 Beta, PP2A B Subunit PR61 Beta, PP2A B Subunit R5 Beta, PPP2R5B, Protein Phosphatase 2A Regulatory Subunit B56 Beta, Serine/Threonine Protein Phosphatase 2A 56 kDa Regulatory Subunit Beta
Terms in Protein Phosphatase-2 Regulatory Subunit-B Beta category
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