Cancer Terms

Protein Tyrosine Phosphatase Epsilon Isoform-2

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Protein Tyrosine Phosphatase Epsilon Isoform-2 Definition

Encoded by human PTPRE Gene (PTP Family), alternative isoform 642-aa Protein Tyrosine Phosphatase Epsilon Isoform 2 is a cytoplasmic nonreceptor-type PTP with a distinct hydrophilic N-terminus and PTP catalytic domains. Alternative isoform 700-aa 81-kDa (precursor) Protein Tyrosine Phosphatase Receptor Type Epsilon Isoform 1 is a type I membrane protein receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains. Studies of the mouse homolog suggest a regulatory role for PTPRE in RAS related signal transduction pathways, cytokine-induced SATA signaling, and activation of voltage-gated K+ channels. (NCI)

Protein Tyrosine Phosphatase Epsilon Isoform-2 Synonyms

Protein Tyrosine Phosphatase Epsilon Isoform-2, HPTPE, PTPE, PTPRE, Protein Tyrosine Phosphatase E Isoform 2, Protein Tyrosine Phosphatase Epsilon Polypeptide

Terms in Protein Tyrosine Phosphatase Epsilon Isoform-2 category



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