Pyroxamide
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Pyroxamide Definition
A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. (NCI04)
Pyroxamide Synonyms
Pyroxamide, Suberoyl-3-aminopyridineamide Hydroxamic Acid, pyroxamide
Terms in Pyroxamide category
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