Cancer Terms

R763

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> Aurora Kinase Inhibitor -> R763

R763 Definition

A water-soluble, synthetic small molecule with potential antineoplastic activity. R763 selectively binds to and inhibits aurora kinases (AKs), a family of serine-threonine kinases that are important regulators of cell division and proliferation, and are overexpressed in certain types of cancer. Inhibition of aurora kinases inhibits cell division and proliferation, as well as induces apoptosis in tumor cells overexpressing AKs.

R763 Synonyms

Aurora Kinase Inhibitor R763, R763

Terms in R763 category



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