R763
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Enzyme Inhibitor ->
Protein Kinase Inhibitor ->
Serine Threonine Kinase Inhibitor ->
Aurora Kinase Inhibitor -> R763
R763 Definition
A water-soluble, synthetic small molecule with potential antineoplastic activity. R763 selectively binds to and inhibits aurora kinases (AKs), a family of serine-threonine kinases that are important regulators of cell division and proliferation, and are overexpressed in certain types of cancer. Inhibition of aurora kinases inhibits cell division and proliferation, as well as induces apoptosis in tumor cells overexpressing AKs.
R763 Synonyms
Aurora Kinase Inhibitor R763, R763
Terms in R763 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.