Cancer Terms

RAB8 Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> G Protein -> Small G Protein -> RAS Superfamily Protein -> RAB8 Protein

RAB8 Protein Definition

RAB8 protein (MEL) contains the four GTP/GDP-binding sites present in all RAS proteins. The putative effector-binding site of MEL is similar to that of RAB/YPT proteins. However, MEL contains a C-terminal CAAX motif characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Members of the RAS superfamily are small GTP/GDP-binding proteins. RAB/YPT family proteins may play a role in transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. (from OMIM 165040 and NCI)

RAB8 Protein Synonyms

RAB8 Protein, MEL, MEL Gene Product, RAS-Related Protein RAB-8

Terms in RAB8 Protein category



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