RAD54B Homolog Protein
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
DNA Repair Protein -> RAD54B Homolog Protein
RAD54B Homolog Protein Definition
Highly expressed in testis and spleen by human RAD54B Gene (SNF2/SWI2 Family), the two isoforms of 910-aa 100-kD nucleoplasmic RAD54B Homolog exhibit significant homology to RAD54 and motifs similar to DNA and RNA helicases. RAD54B binds to double-stranded DNA and displays DNA-associated ATPase activity. RAD54B appears to associate indirectly with RAD51 through its N-terminal domain and may colocalize with RAD54 and BRCA1. Part of a complex involved in meiotic and mitotic homologous DNA recombination repair, RAD54B plays a critical role in targeted integration and recombination in concert with other RAD52 epistasis group members without affecting cell growth, sensitivity to DNA damaging agents, or sister chromatid exchange. (NCI)
RAD54B Homolog Protein Synonyms
RAD54B Homolog, RAD54B, RAD54B Protein
Terms in RAD54B Homolog Protein category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.