Cancer Terms

RAS-Related Protein-RRAS2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> G Protein -> Small G Protein -> RAS Superfamily Protein -> RAS-Related Protein-RRAS2

RAS-Related Protein-RRAS2 Definition

Encoded by human RRAS2 Gene (RAS GTPase Family), ubiquitous 204-aa 23-kDa RAS-Related Protein R-RAS2 is a plasma membrane-associated GTP-binding GTPase that may transduce growth inhibitory signals by exerting an antagonistic effect on a RAS effector. RRAS2 may be posttranslationally modified by palmitoylation and polyisoprenylation. Attachment to the inner surface of plasma membrane may require acylation of a C-terminal cysteine. RRAS2 defects can cause ovarian tumors. (NCI)

RAS-Related Protein-RRAS2 Synonyms

RAS-Related Protein R-RAS2, RAS-Like Protein TC21, RRAS2, Related RAS Viral (R-Ras) Oncogene Homolog 2, TC21

Terms in RAS-Related Protein-RRAS2 category



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