Cancer Terms

RET Finger Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> RET Finger Protein

RET Finger Protein Definition

Encoded by human RFP Gene (TRIM Family), 513-aa 58.5-kDa RET Finger Protein contains a TRIM motif: 3 zinc-binding domains, a RING, a type 1 and type 2 B-box, and a coiled-coil region. Located in the nuclear matrix, RFP interacts with enhancer of polycomb protein, represses gene transcription, and is thought to be involved in male germ cell differentiation. Gene rearrangements with RET produce RET transforming protein, containing the RFP N-terminus with the RET protein tyrosine kinase. (NCI)

RET Finger Protein Synonyms

RET Finger Protein, RFP, Tripartite Motif Protein 27, Tripartite Motif Protein TRIM27, Zinc-Finger Protein RFP

Terms in RET Finger Protein category



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