RUNX1 wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> RUNX1 Gene -> RUNX1 wt Allele

RUNX1 wt Allele Definition

Human RUNX1 wild-type allele is located in the vicinity of 21q22.3 and is approximately 262 kb in length. This allele, which encodes Runt-related transcription factor 1 protein, is involved in both the modulation of transcription by RNA polymerase II and in hematopoiesis. Chronic myelogenous leukemia with or without blastic crisis, acute non-lymphocytic leukemia, T-cell acute lymphocytic leukemia, and myelodysplastic syndrome are all associated with complex chromosomal rearrangements of this gene.

RUNX1 wt Allele Synonyms

RUNX1 wt Allele, AML1, AMLCR1, CBFA2, PEBP2A2, PEBP2aB, RUNX1, Runt-Related Transcription Factor 1 (Acute Myeloid Leukemia 1; AML1 Oncogene) Gene, v-rel Reticuloendotheliosis Viral Oncogene Homolog A, Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-cells 3, p65 (Avian) wt Allele

RUNX1 wt Allele

RUNX1 wt Allele Definition

RUNX1 wt Allele Synonyms

Terms in RUNX1 wt Allele category