Cancer Terms

RXY FXpSXP Motif

Cancer Terms -> Anatomic Structure System or Substance -> Microanatomy -> Macromolecular Structure -> Protein Structure -> Protein Domain -> Ligand Binding Domain -> Protein Binding Domain -> RXY FXpSXP Motif

RXY FXpSXP Motif Definition

The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. RXY/FXpSXP Motif is one of two different binding motifs that are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM)

RXY FXpSXP Motif Synonyms

RXY/FXpSXP Motif, RXY/FXpSXP Domain

Terms in RXY FXpSXP Motif category



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