Cancer Terms

Raf MEK Serine Threonine Kinase Inhibitor RO5126766

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Serine Threonine Kinase Inhibitor -> Raf MEK Serine Threonine Kinase Inhibitor RO5126766

Raf MEK Serine Threonine Kinase Inhibitor RO5126766 Definition

A protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity. Raf/MEK dual kinase Inhibitor RO5126766 specifically inhibits the kinase activities of Raf and MEK, resulting in the inhibition of target gene transcription that promotes malignant transformation of cells. Both Raf and MEK are serine/threonine-specific kinases that respond to extracellular stimuli, such as mitogens, and are involved in the regulation of cellular processes, such as gene expression, mitosis, differentiation, and apoptosis.

Raf MEK Serine Threonine Kinase Inhibitor RO5126766 Synonyms

Raf/MEK Serine/Threonine Kinase Inhibitor RO5126766, RO5126766

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