Cancer Terms

Renal Tumor Antigen

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> Mitogen-Activated Protein Kinase -> Renal Tumor Antigen

Renal Tumor Antigen Definition

Expressed in heart, brain, lung, kidney, pancreas, placenta, liver, and skeletal muscle by human RAGE Gene (MAPK Family), 419-aa cytoplasmic Renal Tumor Antigen is 84% identical overall to the mouse protein (96% identical in the kinase domain) and structurally similar to other MAPKs, including a TEY motif in the activation loop that probably requires autophosphorylation and is required for kinase activity. MOK phosphorylates myelin basic protein. (NCI)

Renal Tumor Antigen Synonyms

Renal Tumor Antigen, MOK Protein Kinase, RAGE, RAGE1

Terms in Renal Tumor Antigen category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.