Cancer Terms

Retinoic Acid Agent

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent

Retinoic Acid Agent Definition

A group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities. A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization. (NCI04)

Retinoic Acid Agent Synonyms

Retinoic Acid Agent, Retinoic Acid and Derivatives, Retinoic Acids, Retinoid, Retinoids, retinoid

Terms in Retinoic Acid Agent category

Acitretin
Adapalene
Alitretinoin
Bexarotene
Carboxyphenyl Retinamide
Etretinate
Fenretinide
Fenretinide Lipid Matrix
Isotretinoin
LGD 1550
Mofarotene
N 2-Carboxyphenyl Retinamide
N 4-Ethoxyphenyl Retinamide
N 4-Hydroxyphenyl 9-Cis-Retinamide
N 4-Methoxyphenyl Retinamide
N Ethyl 9-Cis-Retinamide
Palovarotene
Retinoid 9cUAB30
Retinoid Analogue NRX 195183
Retinyl Acetate
Retinyl Palmitate
Rexinoid NRX 194204
Ro 16-9100
TAC-101
Tamibarotene
Tazarotene
Temarotene
Vitamin A Acid



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