Rexinoid NRX 194204
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Antineoplastic Agent ->
Cell Differentiating Agent ->
Differentiation Inducer ->
Retinoic Acid Agent -> Rexinoid NRX 194204
Rexinoid NRX 194204 Definition
An orally bioavailable synthetic retinoid X receptor (RXR) agonist with potential antineoplastic and anti-inflammatory activities. Rexinoid NRX 194204 selectively binds to and activates RXRs. Because RXRs can form heterodimers with several nuclear receptors, RXR activation by this agent may result in a broad range of gene expression depending on the effector DNA response elements activated. Rexinoid NRX 194204 may inhibit the tumor-necrosis factor (TNF)-mediated release of nitric oxide (NO) and interleukin 6 (IL6) and may inhibit tumor cell proliferation. This agent appears to be less toxic than RAR-selective ligands.
Rexinoid NRX 194204 Synonyms
Rexinoid NRX 194204, AGN194204, NRX194204
Terms in Rexinoid NRX 194204 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.