Rhombotin-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Rhombotin-2

Rhombotin-2 Definition

Rhombotin 2, an LMO (LIM-only) family member that functions in hematopoiesis, is encoded by the LMO2 gene. With two LIM domains and a cysteine-rich motif, rhombotin 2 is part of a multi-protein transcription regulatory complex that includes GATA-1. LMO2 protein binds to the bHLH TAL1 protein and interacts with retinoblastoma binding protein-2, enhancing transcription. Chromosomal translocations involving LMO2 are associated with T-cell leukemias. (from OMIM 180385 and NCI)

Rhombotin-2 Synonyms

Rhombotin 2, Cysteine-Rich Protein TTG-2, LIM Domain Only 2, LIM-Only Protein 2, LMO2, LMO2 Protein, Lim Domain Only 2 Protein, Rhombotin 2 Protein, Rhombotin-Like 1, Rhombotin-Like 1 Protein, T-Cell Translocation Gene 2 Protein, T-Cell Translocation Protein 2, TTG-2 Protein

Rhombotin-2

Rhombotin-2 Definition

Rhombotin-2 Synonyms

Terms in Rhombotin-2 category