Cancer Terms

Ribosomal Protein S6 Kinase Beta-2

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Ribosomal Protein S6 Kinase Beta-2 Definition

Encoded by human RPS6KB2 Gene (S6 Ser/Thr Kinase Family), 482-aa 53-kDa Ribosomal Protein S6 Kinase Beta 2 specifically phosphorylates 40S ribosomal protein S6, the major eukaryotic ribosome substrate of many kinases. S6 phosphorylation is stimulated by growth factors and mitogens; dephosphorylation occurs at growth arrest. S6 may control cell growth and proliferation through the selective translation of specific of mRNA classes. (NCI)

Ribosomal Protein S6 Kinase Beta-2 Synonyms

Ribosomal Protein S6 Kinase Beta 2, 70 kDa Ribosomal Protein S6 Kinase 2, RPS6KB2, Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2, S6 Kinase-Related Kinase, S6K-Beta 2, S6K2, SRK, Serine/Threonine-Protein Kinase 14 Beta, p70 Ribosomal S6 Kinase Beta, p70 S6K Beta, p70-Beta, p70-S6KB, p70S6KB

Terms in Ribosomal Protein S6 Kinase Beta-2 category



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