SIL-SCL Chimeric Protein
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SIL-SCL Chimeric Protein Definition
A chimeric SIL/SCL locus, produced by interstitial deletion between SIL and the 5-prime untranslated region of SCL and disrupting the SCL regulatory region, has been observed. SCL mRNA expression becomes regulated by the SIL promoter, leading to inappropriate SCL expression. This type of rearrangement is frequently seen in T-cell acute lymphoblastic leukemia. (from OMIM 181590 and NCI)
SIL-SCL Chimeric Protein Synonyms
SIL/SCL Chimeric Protein
Terms in SIL-SCL Chimeric Protein category
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