Cancer Terms

SKI-Interacting Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Coactivator -> SKI-Interacting Protein

SKI-Interacting Protein Definition

Encoded by human SNW1 Gene (SNW Family), 536-aa 61.5-kDa nuclear coactivator SKI-Interacting Protein binds to vitamin D receptor ligand-binding domain and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. SNW1 interacts with a region of SKI oncoproteins required for transforming activity and can interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. (NCI)

SKI-Interacting Protein Synonyms

SKI-Interacting Protein, BX42 Homolog, NCOA-62, Nuclear Protein SKIP, Nuclear Receptor Coactivator 62-kD, Nuclear Receptor Coactivator NCOA-62, SKIIP, SKIP, SNW1, SNW1 Protein

Terms in SKI-Interacting Protein category



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