SPINK1 wt Allele

Cancer Terms -> Gene -> Enzyme Inhibitor Gene -> Proteinase Inhibitor Gene -> SPINK1 Gene -> SPINK1 wt Allele

SPINK1 wt Allele Definition

Human SPINK1 wild-type allele is located within 5q32 and is approximately 7 kb in length. This allele, which encodes pancreatic secretory trypsin inhibitor protein, is involved in the inhibition of premature trypsin-catalyzed zymogen activation in the pancreas. Certain allelic variants of the SPINK1 gene cause chronic pancreatitis and confer susceptibility to fibrocalculous pancreatic diabetes. Mutated forms of the pancreatic secretory trypsin inhibitor protein are also involved in the development of tropical calcific pancreatitis.

SPINK1 wt Allele Synonyms

SPINK1 wt Allele, PSTI Gene, Serine Protease Inhibitor, Kazal Type 1 wt Allele

Terms in SPINK1 wt Allele category

---

Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.