Cancer Terms

SU6668

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Angiogenesis Inhibitor -> Angiogenesis Activator Inhibitor -> SU6668

SU6668 Definition

An orally bioavailable receptor tyrosine kinase inhibitor. SU6668 binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. SU6668 also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. (NCI04)

SU6668 Synonyms

SU6668, SU 6668, Sugen SU6668

Terms in SU6668 category



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