Cancer Terms

Safingol Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Protein Kinase C Inhibitor -> Safingol Hydrochloride

Safingol Hydrochloride Definition

The hydrochloride salt of a saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), safingol competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo.

Safingol Hydrochloride Synonyms

Safingol Hydrochloride, (2S,3S)-2-Amino-1,3-Octadecanediol Hydrochloride, 1,3-Octadecanediol, 2-amino-, Hydrochloride, (S-(R*,R*))-, SAFINGOL HYDROCHLORIDE, SPC-100271, Safingol HCl

Terms in Safingol Hydrochloride category



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