Serine-Threonine Kinase-6
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Enzyme ->
Transferase ->
Phosphotransferase ->
Kinase ->
Protein Kinase ->
Serine-Threonine Protein Kinase -> Serine-Threonine Kinase-6
Serine-Threonine Kinase-6 Definition
Expressed in testis, skeletal muscle, thymus, and spleen by human STK6 Gene (Aurora Ser/Thr Kinase Family), 403-aa 45.8-kDa Serine/Threonine Kinase 6 is a phosphorylated cell cycle-regulated kinase localized on centrosomes in interphase cells and at spindle poles in mitosis. Cell cycle-regulated expression accumulates in G2/M and decrease rapidly thereafter. STK6 appears to be involved in cell cycle-regulated microtubule formation and/or stabilization of the spindle pole region during chromosome segregation in anaphase and telophase. STK6 defects are responsible for centrosome aberrations, including aneuploidy. (NCI)
Serine-Threonine Kinase-6 Synonyms
Aurora Kinase A, Aurora Kinase A Protein, Aurora-A, Aurora-Related Kinase 1, Aurora/IPL1-Like Kinase, Aurora/IPL1-Related Kinase 1, Breast-Tumor-Amplified Kinase, IPL1-Related Kinase, STK15, STK6, Serine/Threonine Kinase 15, Serine/Threonine Kinase 6, hARK1
Terms in Serine-Threonine Kinase-6 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.