Serotonin-5-HT-3 Receptor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> Serotonin-5-HT-3 Receptor

Serotonin-5-HT-3 Receptor Definition

Serotonin 5-HT-3 Receptor, encoded by the human HTR3 gene, is one of the several different receptors for serotonin (5-hydroxytryptamine, 5-HT), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Whereas all other known serotonin receptor subtypes are G protein-coupled receptors, this receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Two isoforms, 1/5-HT3R-AS and 2/5-HT3R-AL, are produced by alternative splicing. (From OMIM, Swiss-Prot and NCI)

Serotonin-5-HT-3 Receptor Synonyms

Serotonin 5-HT-3 Receptor, 5-HT-3, 5-HT3R, 5-Hydroxytryptamine (Serotonin) Receptor-3, 5-Hydroxytryptamine 3 Receptor, 5-Hydroxytryptamine Receptor 3, 5-Hydroxytryptamine Receptor 3A, 5-hydroxytryptamine (Serotonin) Receptor 3A, 5HT3R, HTR3, HTR3 Protein, HTR3A, P46098, Serotonin-Gated Ion Channel Receptor

Terms in Serotonin-5-HT-3 Receptor category

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