Sibutramine Hydrochloride
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Sibutramine Hydrochloride Definition
The hydrochloride salt form of sibutramine, a phenethylamine derivative with appetite depressant property. Sibutramine hydrochloride metabolites M1 and M2 competitively inhibit the reuptake of norepinephrine, serotonin, and to a lesser degree dopamine by pre-synaptic nerve terminals, thereby promoting a sense of satiety, leading to a decrease in calorie intake, and possibly an increase in resting metabolic rate. This agent does not exhibit anticholinergic or antihistaminic effects.
Sibutramine Hydrochloride Synonyms
Sibutramine Hydrochloride, BTS 54524, Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)-, Hydrochloride, HSDB 7209, Meridia, SIBUTRAMINE HYDROCHLORIDE
Terms in Sibutramine Hydrochloride category
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