Cancer Terms

Sm 153 Lexidronam Pentasodium

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Radiopharmaceutical Compound -> Radioconjugate -> Sm 153 Lexidronam Pentasodium

Sm 153 Lexidronam Pentasodium Definition

The pentasodium salt of samarium Sm 135 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 135, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases.

Sm 153 Lexidronam Pentasodium Synonyms

Samarium Sm 153 Lexidronam Pentasodium, 153Sm-EDTMP, Quadramet, Samarium Sm 153 Lexidronam, Samarium Sm-153 EDTMP, Samarium-153 EDTMP, Samarium-153 Ethylenediaminetetramethylenephosphonate, Samarium-153 Ethylenediaminetetramethylenephosphonic Acid, Sm 153 Lexidronam Pentasodium, Sm-153 EDTMP

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