Soluble Guanylate Cyclase
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Soluble Guanylate Cyclase Definition
Human Soluble Guanylate Cyclases (Adenylyl Cyclase 4/Guanylyl Cyclase Family) are heterodimeric (alpha/beta) nitric oxide-activated cytoplasmic enzymes that catalyze conversion of GTP to cGMP second messenger. The main receptors for nitric oxide in the cardiovascular system and for nitrovasodilator drugs, alpha/beta interaction is required for guanylyl cyclase activity. (NCI)
Soluble Guanylate Cyclase Synonyms
Soluble Guanylate Cyclase, GUCY, Guanylate Cyclase, Soluble, Soluble Guanylyl Cyclase, sGC
Terms in Soluble Guanylate Cyclase category
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