Cancer Terms

Somatostatin

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Peptide Hormone -> Hypothalmic Hormone -> Somatostatin

Somatostatin Definition

Expressed primarily by human SST Gene (Somatostatin Family) in the hypothalamic median eminence and in pancreatic delta cells, secreted 116-aa 13-kDa (precursor) Somatostatin is an important cyclic tetradecapeptide regulator of endocrine and nervous system function. Somatostatin inhibits release of adenohypophyseal GH, thyrotropin, and corticotropin, pancreatic insulin and glucagon, gastric mucosal gastrin, intestinal mucosal secretin, and renal renin by binding to specific high-affinity cell surface G protein-coupled receptors expressed in a tissue-specific manner. (NCI)

Somatostatin Synonyms

Somatostatin, AY 24910, Growth Hormone Release Inhibiting Factor, Growth Hormone-Inhibiting Hormone, Panhibin, SST, Somatotropin Release Inhibiting Factors

Terms in Somatostatin category



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