Somatostatin Receptor-4

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> Protein Hormone Receptor -> Somatostatin Receptor -> Somatostatin Receptor-4

Somatostatin Receptor-4 Definition

Somatostatin binds to a group of structurally related tissue-specific high-affinity integral membrane GPCRs (family 1), coupled via G proteins to inhibition of adenylyl cyclase. Somatostatin Receptor 4 is specifically expressed in human fetal and adult brain, lung, and stomach, and less in kidney, pituitary, and adrenals. SSTR4 also activates arachidonate release and the MAP kinase cascade. (from OMIM 182454, SWISS-PROT P31391, and NCI)

Somatostatin Receptor-4 Synonyms

Somatostatin Receptor 4, SSTR4

Terms in Somatostatin Receptor-4 category

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