Cancer Terms

Sp1 Transcription Factor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Sp1 Transcription Factor

Sp1 Transcription Factor Definition

Transcription factor SP1 is a DNA-binding protein that interacts with various RNA polymerase II gene promoters containing GC-box elements. It has contiguous zinc finger motifs and requires zinc for sequence-specific binding to DNA. The formation of head segments in Drosophila depends on the homologue of the human transcription factor SP1. (from OMIM 189906 and NCI)

Sp1 Transcription Factor Synonyms

Sp1 Transcription Factor, SP1, Stimulatory Protein 1

Terms in Sp1 Transcription Factor category



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