Cancer Terms

Spermidine-Spermine N1-Acetyltransferase

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Acyltransferase -> Spermidine-Spermine N1-Acetyltransferase

Spermidine-Spermine N1-Acetyltransferase Definition

Encoded by human SAT Gene, 171-aa 20-kDa cytoplasmic Spermidine/Spermine N1-Acetyltransferase is a highly regulated homotetrameric rate-limiting enzyme in the catabolic polyamine metabolism pathway that regulates intracellular polyamine concentration and polyamine transport out of cells. SAT acts on putrescine, spermidine, spermine, N(1)-, and N(8)-acetylspermidine and catalyzes N(1)-acetylation of spermidine and spermine. (NCI)

Spermidine-Spermine N1-Acetyltransferase Synonyms

Spermidine/Spermine N1-Acetyltransferase, Diamine N-Acetyltransferase, EC 2.3.1.57, Putrescine Acetyltransferase, SAT, SPD/SPM acetyltransferase, SSAT, Spermidine N1-Acetyltransferase

Terms in Spermidine-Spermine N1-Acetyltransferase category



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