Splice Site SNP

Cancer Terms -> NCI Administrative Concepts -> Cancer Science -> Miscellaneous Molecular Biology Terms -> Genetic Variation -> Genetic Polymorphism -> Single Nucleotide Polymorphism -> Single Nucleotide Polymorphism in Intronic Sequences -> Splice Site SNP

Splice Site SNP Definition

An inherited single base substitution in a sequence of eukaryotic DNA located in either an acceptor (3' or downstream) or donor (5' or upstream) splice site of a gene. Functional single nucleotide polymorphisms in these intron-exon junctions can cause incorrect RNA splicing which, in turn, alters gene expression.

Splice Site SNP Synonyms

Splice Site SNP

Terms in Splice Site SNP category

Acceptor Splice Site SNP
Donor Splice Site SNP