Cancer Terms

Stefin Family Gene

Cancer Terms -> Gene -> Enzyme Inhibitor Gene -> Proteinase Inhibitor Gene -> Cysteine Proteinase Inhibitor Gene -> Cystatin Superfamily Gene -> Stefin Family Gene

Stefin Family Gene Definition

One of three inhibitory families in the cystatin superfamily (including type 2 cystatins and kininogens), Stefin Family Genes (type 1 cystatins) encode intracellular cysteine thiol protease inhibitors of papain and cathepsins B, H, and L. Cystatin Superfamily proteins contain multiple cystatin-like sequences; some are active cysteine protease inhibitors, while others have lost or perhaps never acquired this activity. (NCI)

Stefin Family Gene Synonyms

Stefin Family Gene, Cystatin 1 Family Gene

Terms in Stefin Family Gene category

CST6 Gene



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