Cancer Terms

T-20

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antiviral Agent -> Anti-HIV Agent -> T-20

T-20 Definition

An antiretroviral peptide with activity against human immunodeficiency virus (HIV) 1. Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41subunit of the viral envelope glycoprotein, thereby preventing conformational changes required for fusion of viral and cellular membranes. This inhibits the fusion of viral and cellular membranes and prevents the virus from entering host cells.

T-20 Synonyms

Enfuvirtide, ENFUVIRTIDE, Fuzeon, T-20

Terms in T-20 category



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