TBP-Associated Factor-11

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> TBP-Associated Factor-11

TBP-Associated Factor-11 Definition

Encoded by human TAF11 Gene (TAF2I Family), 211-aa 23-kDa nuclear TBP-Associated Factor 11 is a small subunit of all TFIID complexes that interacts directly with TBP, interacts with TAFII18, and interacts with TAF13 to form a heterodimer with a structure similar to the histone core structure. TBP and TAFII18 bind to distinct domains of TAF11. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI)

TBP-Associated Factor-11 Synonyms

TBP-Associated Factor 11, TAF11, TAF11 RNA Polymerase II, TAFII28, TATA Box Binding Protein-Associated Factor RNA Polymerase II I 28kD, TBP-Associated Factor 28kDa, TBP-Associated Factor RNA Polymerase II I 28kD, TFIID Subunit p30-Beta, Transcription Initiation Factor TFIID 28 kD Subunit

TBP-Associated Factor-11

TBP-Associated Factor-11 Definition

TBP-Associated Factor-11 Synonyms

Terms in TBP-Associated Factor-11 category