TBP-Associated Factor-13

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Basal Transcription Factor -> TBP-Associated Factor-13

TBP-Associated Factor-13 Definition

Encoded by human TAF13 Gene (TAF2K Family), 124-aa 14-kDa nuclear TBP-Associated Factor 13 is a small subunit associated with a subset of TFIID complexes (TFIID Beta-specific). TAF13 interacts with TBP and with strongly TAF10 and TAF11; TAF10 and TAF11 binding involves distinct TAFII18 domains. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI)

TBP-Associated Factor-13 Synonyms

TBP-Associated Factor 13, TAF13, TAF13 RNA Polymerase II, TAFII18, TATA Box Binding Protein-Associated Factor 18kDa, TBP-Associated Factor 18kDa, Transcription Initiation Factor TFIID 18 kD Subunit

TBP-Associated Factor-13

TBP-Associated Factor-13 Definition

TBP-Associated Factor-13 Synonyms

Terms in TBP-Associated Factor-13 category