TBP-Associated Factor-50kDa
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Basal Transcription Factor -> TBP-Associated Factor-50kDa
TBP-Associated Factor-50kDa Definition
Expressed specifically in male germ cells (testis) by human TAF7L Gene, TBP-Associated Factor 50kDa is a component of TFIID, composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI)
TBP-Associated Factor-50kDa Synonyms
TBP-Associated Factor 50kDa, TAF2Q, TAF7-Like RNA Polymerase II, TAF7L, TATA Box Binding Protein-Associated Factor 50kDa, TATA Box Binding Protein-Associated Factor RNA Polymerase II Q, TBP-Associated Factor RNA Polymerase II Q
Terms in TBP-Associated Factor-50kDa category
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