TBP-Associated Factor-F
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Protein ->
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Basal Transcription Factor -> TBP-Associated Factor-F
TBP-Associated Factor-F Definition
Encoded by human TAF7 Gene (TAF2F Family), ubiquitous 349-aa 40-kDa nuclear TBP-Associated Factor F is a component of TFIID complex (with or without TAFII30) that binds class II promoter TATA boxes and recruits RNA polymerase II and other factors. TAF7 interacts with TAFII250, TAFII100, TAFII28, TAFII20, TAFII18, and multiple transcription activators. TFIID is composed of TBP and many evolutionarily conserved TAFs, which participate in basal transcription, serve as coactivators, and function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. Multimeric protein complex TFIID binds to the core promoter to position polymerase, serves as scaffold for assembly of the transcription complex, and acts as a channel for regulatory signals. (NCI)
TBP-Associated Factor-F Synonyms
TBP-Associated Factor F, TAF2F, TAF7, TAF7 RNA Polymerase II, TAFII55, TATA Box Binding Protein-Associated Factor 55kDa, TATA Box Binding Protein-Associated Factor RNA Polymerase II F 55kD, TATA Box-Binding Protein-Associated Factor 2F, TBP-Associated Factor 55kDa, TBP-Associated Factor RNA Polymerase II F 55kD, Transcription Factor IID Subunit TAFII55, Transcription Initiation Factor TFIID 55 kDa Subunit
Terms in TBP-Associated Factor-F category
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