TCTA wt Allele

Cancer Terms -> Gene -> Cancer Gene -> Tumor Suppressor Gene -> Candidate Tumor Suppressor Gene -> TCTA Gene -> TCTA wt Allele

TCTA wt Allele Definition

Human TCTA wild-type allele is located within 3p21 and is approximately 4 kb in length. This allele encodes T-cell leukemia translocation-associated gene protein. The TCTA gene has been shown exhibit a t(14;21)(q11. 2;q22) chromosomal translocation in T-cell acute lymphoblastic leukemia, resulting in activation of BHLHB1 gene expression. This alteration leads to a leukemogenic effect via the functional inactivation of repressor proteins.

TCTA wt Allele Synonyms

TCTA wt Allele, T-Cell Leukemia Translocation Altered wt Allele

Terms in TCTA wt Allele category

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