Cancer Terms

TFAP2B wt Allele

Cancer Terms -> Gene -> Regulatory Gene -> Transcription Coregulator Gene -> Transcription Coactivator Gene -> TFAP2B Gene -> TFAP2B wt Allele

TFAP2B wt Allele Definition

Human TFAP2B wild-type allele is located within 6p21-p12 and is approximately 25 kb in length. This allele, which encodes transcription factor AP-2 beta protein, is involved in gene expression modulation during ectodermal differentiation. Missense mutations of the wild-type allele can lead to autosomal dominant Char syndrome.

TFAP2B wt Allele Synonyms

TFAP2B wt Allele, AP-2 Beta, AP-2B, AP2-B, AP2-Beta, CHAR, Transcription Factor AP-2 Beta (Activating Enhancer Binding Protein 2 Beta) wt Allele

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